Article
Wavelet-based identification of DNA focal genomic aberrations from single nucleotide polymorphism arrays.
BMC bioinformatics - 11 May 2011
Hur Youngmi, Lee Hyunju
Abstract excerpt
BACKGROUND: Copy number aberrations (CNAs) are an important molecular signature in cancer initiation, development, and progression. However, these aberrations span a wide range of chromosomes, making it hard to distinguish cancer related genes from other genes that are not closely related to cancer but are located in broadly aberrant regions. With the current availability of high-resolution data sets such as...
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