Article
Identification of cancer-driver genes in focal genomic alterations from whole genome sequencing data.
Scientific reports - 9 May 2016
Jang Ho, Hur Youngmi, Lee Hyunju
Abstract excerpt
DNA copy number alterations (CNAs) are the main genomic events that occur during the initiation and development of cancer. Distinguishing driver aberrant regions from passenger regions, which might contain candidate target genes for cancer therapies, is an important issue. Several methods for identifying cancer-driver genes from multiple cancer patients have been developed for single nucleotide polymorphism (SNP)...
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