Establishment and characterization of a new Epstein-Barr virus transformed cell line from a human B cell lymphoma.

doi:10.1007/BF01720278

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Article

Establishment and characterization of a new Epstein-Barr virus transformed cell line from a human B cell lymphoma.

Blut - 1 Mar 1990

Janssen O, Heinze B, Bartram C R, Pawlita M, Binder T, Heimpel H, Diehl K, Kabelitz D

Abstract excerpt

We have established a new cell line from a patient with centrocytic B cell lymphoma. Highly purified peripheral blood B cells from patient DUL (WBC counts 158,000/microliters) were infected in vitro with Epstein-Barr virus (EBV), and CD20+ B cells were cloned into 96 well culture plates with the aid of a cell sorter autoclone device. As shown by GTG-banding and Southern blot analysis, out-growing EBV-positive...

Topics

Antigens, Surface
B-Lymphocytes
Cell Line, Transformed
Cell Nucleus
Cell Transformation, Viral
Chromosome Aberrations
Cytoplasm
DNA, Viral
HLA Antigens
Herpesvirus 4, Human
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Karyotyping

Lymphoma

Male

Middle Aged

Nucleic Acid Hybridization

Phenotype

Source

Open in PubMed

Identifiers

PMID: 2156585
DOI: 10.1007/BF01720278

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2156585-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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