Article
A novel human lymphoma cell line (Deglis) with dual B/T phenotype and gene rearrangements and containing Epstein-Barr virus genomes.
Blood - 1 Jul 1992
al Saati T, Delécluze H J, Chittal S, Brousset P, Magaud J P, Dastugue N, Cohen-Knafo E, Laurent G, Rubin B, Delsol G
Abstract excerpt
We report a new and apparently unique human lymphoma cell line termed Deglis. The line was established from a polymorphic centroblastic lymphoma. The cell line and its source carry a dual B-cell and T-cell phenotype and Epstein-Barr virus (EBV) genomes. Simultaneous expression of B-cell (CD19+, CD20+, CD23+, CD37+) and T-cell (CD2+, CD3+/-, CD7+, CD43+) antigens, activation antigens (CD30+, CDw70+) as well as...
Topics
- Antigens, Differentiation, B-Lymphocyte
- Antigens, Differentiation, T-Lymphocyte
- CD3 Complex
- Gene Expression
- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Gene Rearrangement, delta-Chain T-Cell Antigen Receptor