Phenotypic and cytogenetic characteristics of a new Epstein-Barr virus negative cell line (SKW 4) derived from a B-cell lymphoma.

doi:10.1002/hon.2900010402

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Article

Phenotypic and cytogenetic characteristics of a new Epstein-Barr virus negative cell line (SKW 4) derived from a B-cell lymphoma.

Hematological oncology - 1 Jan 2000

Nilsson K, Klareskog L, Ralph P, Sundström C, Zech L

Abstract excerpt

A new Epstein-Barr virus nuclear antigen (EBNA) negative cell line SKW 4 has been established in vitro from a patient with diffuse histiocytic lymphoma. The SKW 4 seems to be an authentic human tumour cell line as evidenced by its EBV negativity, monoclonality and aneuploidy tested during early in vitro passage. The cell line expresses surface mu and kappa-chains, HLA-DR antigen, C3 and Fc receptors and B-cell...

Topics

Antibodies, Monoclonal
Antigens, Neoplasm
Antigens, Viral
B-Lymphocytes
Cell Line
Chromosome Aberrations
Chromosome Banding
Epstein-Barr Virus Nuclear Antigens
Herpesvirus 4, Human
Humans
Immunoglobulin M

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Karyotyping

Lymphoma

Lymphoma, Non-Hodgkin

Male

Phagocytosis

Phenotype

Receptors, Immunologic

Source

Open in PubMed

Identifiers

PMID: 6329938
DOI: 10.1002/hon.2900010402

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-6329938-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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