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Article

Association between CTLA-4 genetic polymorphisms and susceptibility to osteosarcoma in Chinese Han population.

Endocrine - 1 Mar 2014

He Jinshan, Wang Jingcheng, Wang Daxin, Dai Shanhe, Yv Tangyun, Chen Pengtao, Ma Renshi, Diao Chunyv, Lv Guohua

Abstract excerpt

Osteosarcoma (OS) is the most common malignant primary bone tumor in the world. The cytotoxic T-lymphocyte antigen-4 gene (CTLA-4) is an important candidate gene for influencing the development of OS. This study aimed to investigate the potential association of CTLA-4 genetic polymorphisms with OS risk in Chinese Han population. A total of 415 OS patients and 431 healthy controls were enrolled in this study. The...

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PMID: 24078408
DOI: 10.1007/s12020-013-0050-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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