Article
Toll-like receptor 2 polymorphism and Gram-positive bacterial infections after liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 Sept 2011
Lee Sang-Oh, Brown Robert A, Kang Seung H, Abdel-Massih Rima C, Razonable Raymund R
Abstract excerpt
Toll-like receptor 2 (TLR2) is an immune sensor for gram-positive bacterial cell wall components. Single-nucleotide polymorphisms (SNPs) in the TLR2 gene that impair its function may, therefore, influence the risk and outcomes of gram-positive bacterial infections. In a cohort of 694 liver transplant recipients, we assessed the TLR2 SNP that is translated into an amino acid substitution of arginine for glutamine...
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