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Article

C7 genotype of the donor may predict early bacterial infection after liver transplantation.

Scientific reports - 11 Apr 2016

Zhong Lin, Li Hao, Li Zhiqiang, Shi Baojie, Wang PuSen, Wang ChunGuang, Fan Junwei, Sun Hongcheng, Wang Peiwen, Qin Xuebin, Peng Zhihai

Abstract excerpt

Post-transplantation infection causes high mortality and remains a significant challenge. High clinical risk factors for bacterial infection in recipients are often found in critically ill patients. However, for some recipients, bacterial infections are inevitable. It is conceivable that this susceptibility may be related to the genetics of the donor and recipient. Using expression quantitative trait loci (eQTL)...

Topics

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Area Under Curve
Bacterial Infections
Complement C7
Interleukin-1beta
Liver Failure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver Transplantation

Mannose-Binding Lectin

NLR Family, Pyrin Domain-Containing 3 Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 27063552
DOI: 10.1038/srep24121
PMCID: PMC4827091

Genes

NLRP3
MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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