Article
Association between a functional polymorphism in Toll-like receptor 3 and chronic hepatitis C in liver transplant recipients.
Transplant infectious disease : an official journal of the Transplantation Society - 1 Apr 2013
Lee S-O, Brown R A, Razonable R R
Abstract excerpt
BACKGROUND: Toll-like receptor 3 (TLR3) is implicated in the pathogenesis of viral diseases owing to its ability to recognize viral double-stranded RNA. We hypothesized that single nucleotide polymorphism (SNP) in TLR3 gene that impairs the function of the protein-receptor influences the outcome of hepatitis C virus (HCV) infection after liver transplantation. METHODS: The clinical characteristics of 611 liver...
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