Article
DNA repair genes XPC, XPG polymorphisms: relation to the risk of colorectal carcinoma and therapeutic outcome with Oxaliplatin-based adjuvant chemotherapy.
Molecular carcinogenesis - 1 Oct 2012
Liu Duo, Wu Hui-zhe, Zhang Yi-ning, Kang Hui, Sun Ming-jun, Wang En-hua, Yang Xiu-li, Lian Min-qiong, Yu Zhao-jin, Zhao Lin, Olopade Olufunmilayo I, Wei Min-jie
Abstract excerpt
Xeroderma pigmentosum complementation group C and G (XPC, XPG) play important roles in DNA damage repairing machinery. Genetic variations in the XPC and XPG may be associated with increased risk for colorectal carcinoma (CRC). In this study, we evaluated the relation between the XPC Lys939Gln, XPG Asp1104His polymorphisms, and CRC susceptibility in a population-based case-control study, which included 1,028 CRC...
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