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Article

Colorectal Cancer Carcinogenesis: a Multivariate Genetic Model in a Cohort of Romanian Population.

Clinical laboratory - 1 Apr 2017

Procopciuc Lucia M, Osian Gelu, Iancu Mihaela

Abstract excerpt

BACKGROUND: The molecular mechanism of carcinogenesis of sporadic colorectal cancer (CRC) involves genes with roles in folate metabolism, genes involved in metabolization of carcinogenic compounds from diet and tobacco smoke, and genes related to the DNA repair process. The aim of the study was to examine whether the MTHFRC677T, MTHFR- A1298C, TS-2rpt/3rpt, TS-1494del6bp, NAT2*5C-C481T, NAT2*5A-T341C,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28397463
DOI: 10.7754/Clin.Lab.2016.160821

Genes

NAT2
MTHFR
XRCC1
XRCC3
GSTM1

Variants

Provenance

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