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Article

Genetic Polymorphisms of DNA Repair Pathways in Sporadic Colorectal Carcinogenesis

1 Jan 2019

Abstract excerpt

DNA repair systems play a critical role in maintaining the integrity and stability of the genome, which mainly include base excision repair (BER), nucleotide excision repair (NER), mismatch repair (MMR) and double-strand break repair (DSBR). The polymorphisms in different DNA repair genes that are mainly represented by single-nucleotide polymorphisms (SNPs) can potentially modulate the individual DNA repair...

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Share to Colorectal Cancer Treatments and Studies
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PMID: 31031852
DOI: 10.7150/jca.28406

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