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Article

XPC Lys939Gln polymorphism, smoking and risk of sporadic colorectal cancer among Malaysians.

World journal of gastroenterology - 21 Jun 2013

Ahmad Aizat Abdul Aziz, Siti Nurfatimah Mohd Shahpudin, Aminudin Mustapha Mohd, Ankathil Ravindran

Abstract excerpt

AIM: To investigate the risk association of xeroderma pigmentosum group C (XPC) Lys939Gln polymorphism alone and in combination with cigarette smoking on colorectal cancer (CRC) predisposition. METHODS: Peripheral blood samples of 510 study subjects (255 CRC patients, 255 controls)were collected. DNA was extracted and genotyping was performed using polymerase chain reaction-restriction fragment length...

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Identifiers

PMID: 23801864
DOI: 10.3748/wjg.v19.i23.3623
PMCID: PMC3691041

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XPC

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