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Article

Interferon-alpha triggers B cell effector 1 (Be1) commitment.

PloS one - 29 Apr 2011

de Goër de Herve Marie-Ghislaine, Durali Deniz, Dembele Bamory, Giuliani Massimo, Tran Tu-Anh, Azzarone Bruno, Eid Pierre, Tardieu Marc, Delfraissy Jean-François, Taoufik Yassine

Abstract excerpt

B-cells can contribute to the pathogenesis of autoimmune diseases not only through auto-antibody secretion but also via cytokine production. Therapeutic depletion of B-cells influences the functions and maintenance of various T-cell subsets. The mechanisms governing the functional heterogeneity of B-cell subsets as cytokine-producing cells are poorly understood. B-cells can differentiate into two functionally...

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Identifiers

PMID: 21559410
DOI: 10.1371/journal.pone.0019366
PMCID: PMC3084831

Genes

STAT4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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