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Article

An increase in cancer stem cell population after primary systemic therapy is a poor prognostic factor in breast cancer.

British journal of cancer - 24 May 2011

Lee H E, Kim J H, Kim Y J, Choi S Y, Kim S-W, Kang E, Chung I Y, Kim I A, Kim E J, Choi Y, Ryu H S, Park S Y

Abstract excerpt

BACKGROUND: The cancer stem cell (CSC) hypothesis has important clinical implications for cancer therapeutics because of the proposed role of CSCs in chemoresistance. The aim of this study was to investigate changes in the CSC populations before and after primary systemic therapy (PST) and their prognostic role in human breast cancer. METHODS: Paired samples (before and after PST) of breast cancer tissue were...

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Identifiers

PMID: 21559013
DOI: 10.1038/bjc.2011.159
PMCID: PMC3111169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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