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Article

Breast cancer stem cell markers CD44, CD24 and ALDH1: expression distribution within intrinsic molecular subtype.

Journal of clinical pathology - 1 Nov 2011

Ricardo Sara, Vieira André Filipe, Gerhard Renê, Leitão Dina, Pinto Regina, Cameselle-Teijeiro Jorge F, Milanezi Fernanda, Schmitt Fernando, Paredes Joana

Abstract excerpt

BACKGROUND AND AIM: The study of CD44/CD24 and ALDH1 expression is the most accurate method to identify cancer stem cells (CSC) from breast cancer populations. However, the overlap between CD44(+)CD24(-/low) and ALDH1(high) CSC phenotypes in breast cancer seems to be very small, as well as their distribution among intrinsic breast cancer subtypes. Due to this discrepancy, it is imperative to improve the...

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Aldehyde Dehydrogenase 1 Family
CD24 Antigen
Disease-Free Survival
Hyaluronan Receptors
Isoenzymes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kaplan-Meier Estimate

Neoplastic Stem Cells

Retinal Dehydrogenase

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PMID: 21680574
DOI: 10.1136/jcp.2011.090456

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