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Article

Cancer stem cells and their implication in breast cancer.

European journal of clinical investigation - 1 Jul 2014

Carrasco E, Alvarez Pablo J, Prados José, Melguizo Consolación, Rama Ana R, Aránega Antonia, Rodríguez-Serrano Fernando

Abstract excerpt

BACKGROUND: The cancer stem cell (CSC) hypothesis on the origin of cancer has recently gained considerable support. CSCs are tumour cells with the capacity for self-renewal and differentiation that direct the origin and progression of the disease and may be responsible for relapse, metastasis and treatment failures. DESIGN: This article reviews breast CSCs (BCSCs) phenotyping, clinical implications and clinical...

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PMID: 24766664
DOI: 10.1111/eci.12276

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