Breast cancer stem cells expressing different stem cell markers exhibit distinct biological characteristics.

doi:10.3892/mmr.2016.5899

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Article

Breast cancer stem cells expressing different stem cell markers exhibit distinct biological characteristics.

Molecular medicine reports - 1 Dec 2016

Shao Jun, Fan Wei, Ma Biao, Wu Yiping

Abstract excerpt

Identification and isolation of breast cancer stem cells (CSCs) based on CD44/CD24 expression and/or enzymatic activity of aldehyde dehydrogenase 1 (ALDH1). However, the differences among the CD44+/CD24‑/low cells, ALDH1+ cells and the overlap between the sub‑populations have not been frequently investigated. Thus, it is imperative to improve the understanding of breast CSC with different stem markers....

Topics

Adult
Animals
Biomarkers
Breast Neoplasms
Cell Line, Tumor
Cell Movement
Cell Proliferation
Disease Models, Animal
Female
Fluorescent Antibody Technique
Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Heterografts

Humans

Immunophenotyping

Mice

Neoplastic Stem Cells

Phenotype

Spheroids, Cellular

Source

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Identifiers

PMID: 27840965
DOI: 10.3892/mmr.2016.5899
PMCID: PMC5355694

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