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Cancer stem cells and HER2 positive breast cancer: The story so far

21 Feb 2016

Abstract excerpt

Human Epidermal Growth Factor Receptor type 2 (HER2) gene amplification and/or protein overexpression is observed in patients suffering from HER2+ breast cancer. This subtype of breast cancer has improved prognosis due to availability of anti-HER2 therapy. However, drug resistance and tumor recurrence still remains a major concern. Cancer Stem Cells (CSCs) are believed to constitute the subset of cell population...

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PMID: 30123819
DOI: 10.1016/j.gendis.2016.02.002

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