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Article

GSTM1 and GSTT1 copy number variation in population-based studies of endometrial cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2011

Karageorgi Stalo, Prescott Jennifer, Wong Jason Y Y, Lee I-Min, Buring Julie E, De Vivo Immaculata

Abstract excerpt

BACKGROUND: Glutathione S-transferases (GST) detoxify a broad range of carcinogenic metabolites and lack of GSTM1 and GSTT1 activity due to gene deletions are prevalent. The associations of GSTM1 and GSTT1 polymorphisms with endometrial cancer risk have been inconsistent. METHODS: We investigated gene dosage effects of GSTM1 and GSTT1 copy number in 441 endometrial cancer cases and 1,237 matched controls selected...

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Source

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Identifiers

PMID: 21558497
DOI: 10.1158/1055-9965.EPI-11-0190
PMCID: PMC3157698

Genes

GSTT1
GSTM1
IMPACT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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