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Article

Association of Selected Genetic Variants in CYP1A1, CYP2D6, NAT1 and NAT2 with Endometrial Cancer Risk: A Preliminary Case-Control Study.

International journal of molecular sciences - 25 Jun 2026

Skrzypek Maciej, Gogolewska Monika, Bieńkiewicz Andrzej, Wójcik-Krowiranda Katarzyna, Majsterek Ireneusz, Kabziński Jacek

Abstract excerpt

Cancer risk may be influenced by genetic variation and altered expression of xenobiotic-metabolizing enzymes, yet their role in endometrial cancer remains incompletely understood. This study evaluated the association between four polymorphisms in xenobiotic metabolism-related genes CYP1A1 rs1799814, CYP2D6 rs3892097, NAT1 rs72554606, and NAT2 rs1799930 and the risk of endometrial cancer, and assessed CYP1A1 and...

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Source

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Identifiers

PMID: 42450020
DOI: 10.3390/ijms27135747
PMCID: PMC13362363

Genes

CYP1A1
NAT2
NAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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