Article
Functional polymorphisms in cell death pathway genes FAS and FAS ligand and risk of prostate cancer in a Chinese population.
The Prostate - 1 Jul 2011
Shao Pengfei, Ding Qi, Qin Chao, Wang Meilin, Tang Jialin, Zhu Jian, Chen Jiawei, Cao Qiang, Li Jie, Xu Bin, Zhang Zhengdong, Zhang Wei, Yin Changjun
Abstract excerpt
BACKGROUND: Apoptosis is the physiological mechanism of programmed cell death and abnormal regulation of this pathway can lead to carcinogenesis. We hypothesized that the FAS -1377G>A, -670A>G, and FASL -844T>C polymorphisms are associated with risk of prostate cancer (PCa). MATERIALS AND METHODS: We genotyped polymorphisms in a hospital-based case-control study of 602 patients diagnosed with PCa and 703...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.