Article
FAS promoter polymorphisms and cancer risk: a meta-analysis based on 34 case-control studies.
Carcinogenesis - 1 Mar 2009
Zhang Zhizhong, Xue Hengchuan, Gong Weida, Wang Meilin, Yuan Lin, Han Suping, Zhang Zhengdong
Abstract excerpt
FAS is a cell surface receptor involved in apoptotic signal transmission and plays important roles in the etiology of cancer. The -1377G>A and -670A>G polymorphisms of the FAS gene influence the FAS transcription and have been implicated in cancer risk. However, the results from the published studies on the association between these two FAS polymorphisms and cancer risk are conflicting. To derive a more precise...
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