Article
Assessment of the Link of ABCB1 and NR3C1 gene polymorphisms with the prednisolone resistance in pediatric nephrotic syndrome patients of Bangladesh: A genotype and haplotype approach.
Journal of advanced research - 1 Nov 2021
Parvin Most Nazma, Aziz Md Abdul, Rabbi Sikder Nahidul Islam, Al-Mamun Mir Md Abdullah, Hanif Mohammed, Islam Md Saiful, Islam Mohammad Safiqul
Abstract excerpt
Introduction: Nephrotic syndrome is a common pediatric kidney disease. Investigations on several genetic polymorphisms revealed an inconsistent influence on the resistance of patients to steroids. Objectives: This study aimed to identify the association of ABCB1 (1236C > T, 2677G > T, 3435C > T), NR3C1 (rs10482634, rs6877893), and CYP3A5 (CYP3A5*3) gene polymorphism as well as sociodemographic and...
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