Article
ABCB1 polymorphisms and steroid treatment in children with idiopathic nephrotic syndrome.
British journal of biomedical science - 1 Jan 2017
Safan Manal A, Elhelbawy Nesreen G, Midan Dina A, Khader Heba F
Abstract excerpt
BACKGROUND: The most common cause of nephrotic syndrome (NS) is idiopathic nephrotic syndrome (INS), also called nephrosis. Although most patients respond to steroid therapy, there is unequal response to treatment suggesting the involvement of genetic factors. The current study was conducted to evaluate the influence of two single nucleotide polymorphisms (SNPs) in ABCB1 (C3435T and C1236T) on the steroid...
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