Article
Polymorphic variants of MIF gene and prognosis in steroid therapy in children with idiopathic nephrotic syndrome.
Acta biochimica Polonica - 1 Jan 2014
Świerczewska Monika, Ostalska-Nowicka Danuta, Kempisty Bartosz, Szczepankiewicz Aleksandra, Nowicki Michał
Abstract excerpt
UNLABELLED: Nephrotic syndrome (NS) is the most common reason of proteinuria in children and can be caused by the pathology of renal glomeruli. Steroid therapy is typically used in this disorder. It has been shown that MIF is a cytokine which counteracts the immunosuppressive properties of glucocorticoids. The aim of this study was looking for a correlation between MIF polymorphisms and genetic susceptibility to...
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