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Article

The BRAF mutation is associated with the prognosis in colorectal cancer.

Journal of cancer research and clinical oncology - 1 Nov 2014

Ahn Tae Sung, Jeong Dongjun, Son Myoung Won, Jung Haeil, Park Soyoung, Kim Hyungjoo, Bae Sang Byung, Kim Han Jo, Jeon Young-Woo, Lee Moon Soo, Baek Moo-Jun

Abstract excerpt

BACKGROUND: Two members of the Ras/Raf signaling pathway, KRAS and B-raf, are suspected to be involved in the stepwise progression of colorectal cancer (CRC) tumorigenesis. OBJECTIVE: We compared the KRAS and BRAF mutation status of CRC patients with their clinicopathological characteristics and examined the effect of mutation status on survival rates. METHODS: DNA was extracted from 164 samples, and the mutation...

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Source

Identifiers

PMID: 24942334
DOI: 10.1007/s00432-014-1735-y

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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