Article
Sex-specific splicing in Drosophila: widespread occurrence, tissue specificity and evolutionary conservation.
Genetics - 1 Feb 2009
Telonis-Scott Marina, Kopp Artyom, Wayne Marta L, Nuzhdin Sergey V, McIntyre Lauren M
Abstract excerpt
Many genes in eukaryotic genomes produce multiple transcripts through a variety of molecular mechanisms including alternative splicing. Alternatively spliced transcripts often encode functionally distinct proteins, indicating that gene regulation at this level makes an important contribution to organismal complexity. The multilevel splicing cascade that regulates sex determination and sex-specific development in...
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