Article
Personality as an intermediate phenotype for genetic dissection of alcohol use disorder.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2018
Oreland Lars, Lagravinese Gianvito, Toffoletto Simone, Nilsson Kent W, Harro Jaanus, Robert Cloninger C, Comasco Erika
Abstract excerpt
Genetic and environmental interactive influences on predisposition to develop alcohol use disorder (AUD) account for the high heterogeneity among AUD patients and make research on the risk and resiliency factors complicated. Several attempts have been made to identify the genetic basis of AUD; however, only few genetic polymorphisms have consistently been associated with AUD. Intermediate phenotypes are expected...
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