Article
A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.
Journal of psychiatric research - 1 Nov 2011
Wang Ke-Sheng, Liu Xuefeng, Zhang Qunyuan, Pan Yue, Aragam Nagesh, Zeng Min
Abstract excerpt
Family, twin and adoption studies have clearly demonstrated that genetic factors are important in modulating the vulnerability to alcohol dependence. Several genome-wide association (GWA) studies of alcohol dependence have been conducted; however, few loci have been replicated. A meta-analysis was performed on two GWA studies of 1283 cases of alcohol dependence and 1416 controls in Caucasian populations. Through...
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