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Article

ENU mutagenesis to generate genetically modified rat models.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010

van Boxtel Ruben, Gould Michael N, Cuppen Edwin, Smits Bart M G

Abstract excerpt

The rat is one of the most preferred model organisms in biomedical research and has been extremely useful for linking physiology and pathology to the genome. However, approaches to genetically modify specific genes in the rat germ line remain relatively scarce. To date, the most efficient approac...

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PMID: 20013232
DOI: 10.1007/978-1-60327-389-3_11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20013232-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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