Article
Zinc-finger nucleases: new strategies to target the rat genome.
Clinical science (London, England : 1979) - 6 Jul 2010
Geurts Aron M, Moreno Carol
Abstract excerpt
The importance of genetic laboratory models, such as mice and rats, becomes evident when there is a poor understanding of the nature of human disease. Many rat models for human disease, created over the years by phenotype-driven strategies, now provide a foundation for the identification of their genetic determinants. These models are especially valuable with the emerging need for validation of genes found in...
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