Reversion of thermosensitive splicing defect of Moloney murine sarcoma virus ts110 by oversplicing of viral RNA.

doi:10.1128/JVI.64.3.1378-1382.1990

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Article

Reversion of thermosensitive splicing defect of Moloney murine sarcoma virus ts110 by oversplicing of viral RNA.

Journal of virology - 1 Mar 1990

Hamelin R, Honore N, Sergiescu D, Singh B, Gerfaux J, Arlinghaus R B

Abstract excerpt

Moloney murine sarcoma virus ts110 possesses a thermosensitive splicing defect. By continuously growing nonproducer cells at the nonpermissive temperature, a new class of revertant cells, termed 6m3, that had lost the thermosensitive splicing defect was produced, and six distinct clones were sele...

Topics

Animals
Cell Line
DNA, Viral
Moloney murine sarcoma virus
Mutation
RNA Splicing
RNA, Viral
Sarcoma Viruses, Murine
Single-Strand Specific DNA and RNA Endonucleases
Temperature
Viral Proteins

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