Article
Regulation of RNA splicing in gag-deficient mutants of Moloney murine sarcoma virus MuSVts110.
Journal of virology - 1 Apr 1990
De Mars M, Sterner D A, Chiocca S M, Biggart N W, Murphy E C
Abstract excerpt
We investigated whether the MuSVts110 gag gene product (P58gag) can regulate the novel growth temperature dependence of MuSVts110 RNA splicing. MuSVts110 mutants with either frameshifts or deletions in the gag gene were tested for their ability to maintain the MuSVts110 splicing phenotype. Only small decreases in splicing efficiency and no changes in the thermosensitivity of viral RNA splicing were observed in...
Topics
- Animals
- Gene Expression Regulation, Viral
- Gene Products, gag
- Genes, gag
- Moloney murine sarcoma virus
- Mutagens
- Mutation
- Nickel
- RNA Splicing
- RNA, Viral
- Sarcoma Viruses, Murine
