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Article

A temperature-sensitive phenotype of avian myeloblastosis virus: determinants that influence the production of viral mRNAs.

Journal of virology - 1 Feb 1990

Schirm S, Moscovici G, Bishop J M

Abstract excerpt

The oncogene v-myb of avian myeloblastosis virus is expressed from an mRNA that arises by splicing of the viral genome. In previous work, we described a mutant strain of avian myeloblastosis virus (tsAMV) that elicits temperature-sensitive transformation and suggested that the mutation affects production of the mRNA for v-myb. We now report that the principal determinant of the biochemical phenotype of tsAMV is a...

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Identifiers

PMID: 2153241
DOI: 10.1128/JVI.64.2.767-773.1990
PMCID: PMC249171

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