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Article

The Moloney murine sarcoma virus ts110 5' splice site signal contributes to the regulation of splicing efficiency and thermosensitivity.

Journal of virology - 1 Sept 1996

Ainsworth J R, Rossi L M, Murphy E C

Abstract excerpt

The 5' splice site signal (5'ss) in Moloney murine sarcoma virus ts110 (MuSVts110) RNA was found to participate in the regulation of its splicing phenotype. This 5'ss (CAG/GUAGGA) departs from the mammalian consensus (CAG/GURAGU) at positions +4 and +6, both of which base pair with U1 and U6 small nuclear RNAs during splicing. A doubling in splicing efficiency and near elimination of the splicing...

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Identifiers

PMID: 8709285
DOI: 10.1128/JVI.70.9.6474-6478.1996
PMCID: PMC190683

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