Article
Serotonin transporter gene polymorphisms and brain function during emotional distraction from cognitive processing in posttraumatic stress disorder.
BMC psychiatry - 5 May 2011
Morey Rajendra A, Hariri Ahmad R, Gold Andrea L, Hauser Michael A, Munger Heidi J, Dolcos Florin, McCarthy Gregory
Abstract excerpt
BACKGROUND: Serotonergic system dysfunction has been implicated in posttraumatic stress disorder (PTSD). Genetic polymorphisms associated with serotonin signaling may predict differences in brain circuitry involved in emotion processing and deficits associated with PTSD. In healthy individuals, common functional polymorphisms in the serotonin transporter gene (SLC6A4) have been shown to modulate amygdala and...
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