Article
Serotonin polymorphisms and posttraumatic stress disorder in a trauma exposed African American population.
Depression and anxiety - 1 Jan 2009
Mellman Thomas A, Alim Tanya, Brown Denver D, Gorodetsky Elena, Buzas Beata, Lawson William B, Goldman David, Charney Dennis S
Abstract excerpt
BACKGROUND: Genetic polymorphisms that influence serotonin (5-hydroxytryptamine, 5HT) neurotransmission are candidates for contributing to susceptibility to posttraumatic stress disorder (PTSD). The objective of our study was to determine if a variable length polymorphism for the promoter regions of the 5HT transporter (5HTTLPR), and/or a substitution polymorphism in the promoter region for the 5HT2A receptor,...
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