Article
Association study of trauma load and SLC6A4 promoter polymorphism in posttraumatic stress disorder: evidence from survivors of the Rwandan genocide.
The Journal of clinical psychiatry - 1 May 2010
Kolassa Iris-Tatjana, Ertl Verena, Eckart Cindy, Glöckner Franka, Kolassa Stephan, Papassotiropoulos Andreas, de Quervain Dominique J-F, Elbert Thomas
Abstract excerpt
OBJECTIVE: As exposure to different types of traumatic stressors increases, the occurrence of posttraumatic stress disorder (PTSD) increases. However, because some people exhibit either surprising resilience or high vulnerability, further influencing factors have been conjectured, such as gene-environment interactions. The SLC6A4 gene, which encodes serotonin transporter, has been identified as predisposing...
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