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Article

Genetic risk mechanisms of posttraumatic stress disorder in the human brain.

Journal of neuroscience research - 1 Jan 2018

Bharadwaj Rahul A, Jaffe Andrew E, Chen Qiang, Deep-Soboslay Amy, Goldman Aaron L, Mighdoll Michelle I, Cotoia John A, Brandtjen Anna C, Shin JooHeon, Hyde Thomas M, Mattay Venkata S, Weinberger Daniel R, Kleinman Joel E

Abstract excerpt

Posttraumatic stress disorder (PTSD) follows exposure to a traumatic event in susceptible individuals. Recently, genome-wide association studies have identified a number of genetic sequence variants that are associated with the risk of developing PTSD. To follow up on identifying the molecular mechanisms of these risk variants, we performed genotype to RNA sequencing-derived quantitative expression (whole gene,...

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Identifiers

PMID: 27775175
DOI: 10.1002/jnr.23957

Genes

PDZD8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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