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Article

The relationship between combat-related posttraumatic stress disorder and the 5-HTTLPR/rs25531 polymorphism.

Depression and anxiety - 21 Dec 2011

Wang Zhewu, Baker Dewleen G, Harrer Judith, Hamner Mark, Price Matthew, Amstadter Ananda

Abstract excerpt

BACKGROUND: Empirical evidence suggests that there is a significant genetic influence in the development of posttraumatic stress disorder (PTSD). The serotonin transporter (5-HTT) gene (SLC6A4) has been identified as a prime candidate for the development of the disorder, as 5-HTT is a working target for selective serotonin reuptake inhibitors (SSRIs), first line treatment agents for PTSD. Several studies have...

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Identifiers

PMID: 21818827
DOI: 10.1002/da.20872
PMCID: PMC3419583

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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