Article
SLC6A4 methylation modifies the effect of the number of traumatic events on risk for posttraumatic stress disorder.
Depression and anxiety - 1 Aug 2011
Koenen Karestan C, Uddin Monica, Chang Shun-Chiao, Aiello Allison E, Wildman Derek E, Goldmann Emily, Galea Sandro
Abstract excerpt
BACKGROUND: Posttraumatic stress disorder (PTSD) is a common and debilitating mental disorder that occurs following exposure to a traumatic event. However, most individuals do not develop PTSD following even a severe trauma, leading to a search for new variables, such as genetic and other molecular variation, associated with vulnerability and resilience in the face of trauma exposure. METHOD: We examined whether...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- DNA Methylation
- Depression
- Genetic Predisposition to Disease
- Genotype
- Health Surveys
- Humans
- Interview, Psychological