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Article

Extensive epigenetic reprogramming in human somatic tissues between fetus and adult

5 May 2011

Abstract excerpt

BACKGROUND: Development of human tissue is influenced by a combination of intrinsic biological signals and extrinsic environmental stimuli, both of which are mediated by epigenetic regulation, including DNA methylation. However, little is currently known of the normal acquisition or loss of epigenetic markers during fetal and postnatal development. RESULTS: The DNA methylation status of over 1000 CpGs located in...

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PMID: 21545704
DOI: 10.1186/1756-8935-4-7

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