Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Slug Is Increased in Vascular Remodeling and Induces a Smooth Muscle Cell Proliferative Phenotype.

PloS one - 1 Jan 2016

Coll-Bonfill Núria, Peinado Victor I, Pisano María V, Párrizas Marcelina, Blanco Isabel, Evers Maurits, Engelmann Julia C, García-Lucio Jessica, Tura-Ceide Olga, Meister Gunter, Barberà Joan Albert, Musri Melina M

Abstract excerpt

OBJECTIVE: Previous studies have confirmed Slug as a key player in regulating phenotypic changes in several cell models, however, its role in smooth muscle cells (SMC) has never been assessed. The purpose of this study was to evaluate the expression of Slug during the phenotypic switch of SMC in vitro and throughout the development of vascular remodeling. METHODS AND RESULTS: Slug expression was decreased during...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Dedifferentiation
Share to Hypertension, Pulmonary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myocytes, Smooth Muscle

Share to Pulmonary Artery

Share to Snail Family Transcription Factors

Share to Transforming Growth Factor beta1

Share to Vascular Remodeling

Source

Open in PubMed Open full text

Identifiers

PMID: 27441378
DOI: 10.1371/journal.pone.0159460
PMCID: PMC4956159

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Slug Is Increased in Vascular Remodeling and Induces a Smooth Muscle Cell Proliferative Phenotype.PMID 27441378Read ↗

Noncoding RNAs in smooth muscle cell homeostasis: implications in phenotypic switch and vascular disorders.Semantic proximity Read ↗

DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation.Semantic proximity Read ↗

Six Shades of Vascular Smooth Muscle Cells Illuminated by KLF4 (Krüppel-Like Factor 4).Semantic proximity Read ↗

Non-coding RNAs: key regulators of smooth muscle cell fate in vascular disease.Semantic proximity Read ↗

Vascular injury activates the ELK1/SND1/SRF pathway to promote vascular smooth muscle cell proliferative phenotype and neointimal hyperplasia.Semantic proximity Read ↗

Transcriptional regulation of vascular smooth muscle cell proliferation, differentiation and senescence: Novel targets for therapy.Semantic proximity Read ↗

MEF2C-MYOCD and Leiomodin1 Suppression by miRNA-214 Promotes Smooth Muscle Cell Phenotype Switching in Pulmonary Arterial Hypertension.Semantic proximity Read ↗

A regulator of G protein signaling 5 marked subpopulation of vascular smooth muscle cells is lost during vascular diseaseSemantic proximity Read ↗

How do microRNAs affect vascular smooth muscle cell biology?Semantic proximity Read ↗

Discovery of Transacting Long Noncoding RNAs That Regulate Smooth Muscle Cell Phenotype.Semantic proximity Read ↗

Expressional regulation of smooth muscle cell-specific genes in association with phenotypic modulation.Semantic proximity Read ↗

Redistribution of the chromatin remodeler Brg1 directs smooth muscle–derived adventitial progenitor–to–myofibroblast differentiation and vascular fibrosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.