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Article

Polymeric sequences reveal a functional interrelationship between hydrophobicity and length of signal peptides.

The Journal of biological chemistry - 15 Feb 1990

Chou M M, Kendall D A

Abstract excerpt

We have examined the hydrophobicity component of signal peptide function using polymeric sequences in combination with cassette mutagenesis. Using homopolymeric units of either isoleucine, leucine, valine or alanine to replace the natural core segment of the Escherichia coli alkaline phosphatase signal peptide, the hydrophobicity requirements for export and processing were delineated. The transport properties of...

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PMID: 2154463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Polymeric sequences reveal a functional interrelationship between hydrophobicity and length of signal peptides.PMID 2154463Read ↗

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