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Article

Mutations eliminating the protein export function of a membrane-spanning sequence.

The Journal of biological chemistry - 18 Nov 1994

Lee E, Manoil C

Abstract excerpt

Individual membrane protein spanning sequences can promote protein export. To help define the sequence features necessary for this action, we identified mutations disrupting export mediated by the first spanning sequence (TM1) of the Escherichia coli serine chemoreceptor. Mutant spanning sequences were generated and characterized using beta-galactosidase and alkaline phosphatase gene fusions. The protein export...

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PMID: 7961839

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