Article
Two linked hairy/Enhancer of split-related zebrafish genes, her1 and her7, function together to refine alternating somite boundaries.
Development (Cambridge, England) - 1 Aug 2002
Henry Clarissa A, Urban Michael K, Dill Kariena K, Merlie John P, Page Michelle F, Kimmel Charles B, Amacher Sharon L
Abstract excerpt
The formation of somites, reiterated structures that will give rise to vertebrae and muscles, is thought to be dependent upon a molecular oscillator that may involve the Notch pathway. hairy/Enhancer of split related [E(spl)]-related (her or hes) genes, potential targets of Notch signaling, have been implicated as an output of the molecular oscillator. We have isolated a zebrafish deficiency, b567, that deletes...
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