Unbiased characterization of the larval zebrafish enteric nervous system at a single cell transcriptomic level

doi:10.1016/j.isci.2023.107070

Article

Unbiased characterization of the larval zebrafish enteric nervous system at a single cell transcriptomic level

8 Jun 2023

Abstract excerpt

The enteric nervous system (ENS) regulates many gastrointestinal functions including peristalsis, immune regulation and uptake of nutrients. Defects in the ENS can lead to severe enteric neuropathies such as Hirschsprung disease (HSCR). Zebrafish have proven to be fruitful in the identification of genes involved in ENS development and HSCR pathogenesis. However, composition and specification of enteric neurons...

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