Article
Possible involvement of ubiquitin function and ATP requirement in the development of thermotolerance in mammalian cells.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group - 1 Jan 2000
Mizuno S, Ohkawara A, Suzuki K, Yamakawa Y
Abstract excerpt
Thermotolerance under chronic exposure to moderate hyperthermia at 41 degrees C was hardly induced in the mouse temperature-sensitive mutant ts85 cells, in contrast to the parental wild-type FM3A cells. Thermotolerance was induced at a reduced level in the mutant cells compared with the wild-type...
Topics
- 2,4-Dinitrophenol
- Adenosine Triphosphate
- Animals
- Cell Line
- Cell Survival
- Cycloheximide
- Deoxyglucose
- Dinitrophenols
- Hot Temperature
- Mutation
- Proteins
- Ubiquitins