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Article

Cellular diversity within embryonic stem cells: pluripotent clonal sublines show distinct differentiation potential.

Journal of cellular and molecular medicine - 1 Mar 2012

Martinez Yannick, Béna Frédérique, Gimelli Stefania, Tirefort Diderik, Dubois-Dauphin Michel, Krause Karl-Heinz, Preynat-Seauve Olivier

Abstract excerpt

Embryonic stem cells (ESC), derived from the early inner cell mass (ICM), are constituted of theoretically homogeneous pluripotent cells. Our study was designed to test this concept using experimental approaches that allowed characterization of progenies derived from single parental mouse ESC. Flow cytometry analysis showed that a fraction of ESC submitted to neural differentiation generates progenies that escape...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21535399
DOI: 10.1111/j.1582-4934.2011.01334.x
PMCID: PMC3822923

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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